{"id":13,"date":"2026-05-08T15:25:32","date_gmt":"2026-05-08T15:25:32","guid":{"rendered":"http:\/\/sicurezzaanimaliticino.ch\/?page_id=13"},"modified":"2026-05-10T13:20:24","modified_gmt":"2026-05-10T13:20:24","slug":"antikoagulierende-rodentizide","status":"publish","type":"page","link":"https:\/\/sicurezzaanimaliticino.ch\/de\/rodenticidi-anticoagulanti\/","title":{"rendered":"Antikoagulante Rodentizide"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"13\" class=\"elementor elementor-13\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9a83b5d e-flex e-con-boxed e-con e-parent\" data-id=\"9a83b5d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<h2 data-interaction-id=\"3989ee2\" class=\"e-heading-base\">RODENTIZIDE MIT ANTIKOAGULANTER WIRKUNG<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-31aa5f3 e-flex e-con-boxed e-con e-parent\" data-id=\"31aa5f3\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-1740c2a e-con-full e-flex e-con e-child\" data-id=\"1740c2a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"eeb6e36\"><strong id=\"e-mozov5lc-wo7optr\">1. GENERATION<\/strong> <br><br>Warfarin (D)<br>Clorofacinon (I) <br>Cumatetralil (D)<br>Difacinon (I)<br>Cumaclor (D)<\/p>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8c98ca5 e-con-full e-flex e-con e-child\" data-id=\"8c98ca5\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"f8a9420\"><strong id=\"e-mozovd5j-cc8hvqf\">2. GENERATION<\/strong><br><br>Difenacoum (D)<br>Bromadiolon (D)<br>Flocumafen (I)<\/p>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3d9cc8c e-con-full e-flex e-con e-child\" data-id=\"3d9cc8c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"1f34631\"><strong id=\"e-mozovm8y-az6d81r\">3. GENERATION<\/strong><br><br>Brodifacoum (D)<br>Difetialon (T)<\/p>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-76d6e7c e-con-full e-flex e-con e-child\" data-id=\"76d6e7c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"b9e8c04\"><strong id=\"e-mozow6lf-thxfgvp\">LEGENDA<\/strong><br><br>D = Dicumarol-Derivat<br>I = Indandionderivat<br>T = Derivat von Tiocumarol<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f23c817 e-flex e-con-boxed e-con e-parent\" data-id=\"f23c817\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<h2 data-interaction-id=\"09a9440\" class=\"e-heading-base\">ANTIKOAGULANTEN-RODENTIZIDE - Handelsprodukte<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a6f405b e-flex e-con-boxed e-con e-parent\" data-id=\"a6f405b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-4f3d0ac e-con-full e-flex e-con e-child\" data-id=\"4f3d0ac\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"983bae2\"><strong id=\"e-mozowka7-bu9sv84\">Esche<\/strong><br>Typischerweise auf Getreidebasis, je nach Nagetier und Ort der Bek\u00e4mpfung unterschiedlich zubereitet. <br>Konzentrationen von 25 ppm (Difetialon) bis 250 ppm (Warfarin)<\/p>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b01123f e-con-full e-flex e-con e-child\" data-id=\"b01123f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"19e77e8\">Konzentrieren<br>Zur Zubereitung von K\u00f6dern. Frei verk\u00e4uflich: Chlorphacinon 2,5 g\/l Warfarin 10 g\/l<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-bc655e0 e-flex e-con-boxed e-con e-parent\" data-id=\"bc655e0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<h2 data-interaction-id=\"c3a802c\" class=\"e-heading-base\">ANTIKOAGULANTIEN - KINETIK<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-f74383d e-flex e-con-boxed e-con e-parent\" data-id=\"f74383d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"060bf8d\">1- Langsame, aber hohe orale Absorption<br>2- Lange Verweildauer im Blut, hohe Bindung an Albumin 98-99%, Plasmahalbwertszeit: Warfarin: 14,5 Stunden (Hund), Brodifacoum: 140 Stunden (Hund)<br>3- Langsamer oxidativer Metabolismus (Cytochrom P450)<br>4- An enterohepatischen Kreislauf<br>5- Hohe Affinit\u00e4t zu hepatischen Rezeptoren (II-III Gen.)<br>6- Lange Verweildauer in der Leber (II-III Gen.) Chlorfacinon \u00bb 30 Tage Difenacoum \u00bb 100 Tage Brodifacoum \u00bb 180 Tage<br>7- Langsame renale Ausscheidung unver\u00e4nderter Verbindungen und Metaboliten<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d120138 e-flex e-con-boxed e-con e-parent\" data-id=\"d120138\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<h2 data-interaction-id=\"295fafe\" class=\"e-heading-base\">FOLGEN<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8b6d97b e-flex e-con-boxed e-con e-parent\" data-id=\"8b6d97b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8b3bb53 e-con-full e-flex e-con e-child\" data-id=\"8b3bb53\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"edca29b\">\u2022 Progressive Reduktion der Vit. K-Konzentration in der Leber (Vorr\u00e4te f\u00fcr ca. 24 Stunden)<br>\u2022 Progressive Reduktion der aktivierten PPSB-Faktoren (II, VII, IX und X)<\/p>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5911696 e-con-full e-flex e-con e-child\" data-id=\"5911696\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"aee5198\">Schwere Blutungen schon bei kleinen Traumata, die sich ereignen, oder nach wiederholter Exposition oder nach 2-3 Tagen nach einmaliger Einnahme von Produkten der zweiten und dritten Generation<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-122be6c e-flex e-con-boxed e-con e-parent\" data-id=\"122be6c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<h2 data-interaction-id=\"590d04f\" class=\"e-heading-base\">Sekund\u00e4rvergiftung<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9b177fb e-flex e-con-boxed e-con e-parent\" data-id=\"9b177fb\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"f218a0c\">Die M\u00f6glichkeit einer Sekund\u00e4rvergiftung ist auch f\u00fcr Wildtiere ziemlich hoch<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-52d4a35 e-flex e-con-boxed e-con e-parent\" data-id=\"52d4a35\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<h2 data-interaction-id=\"ffa89ca\" class=\"e-heading-base\">Symptomatologie<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c1c537a e-flex e-con-boxed e-con e-parent\" data-id=\"c1c537a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"97f6606\">Klinische Manifestationen: 2 \u2013 10 Tage nach der Einnahme<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-19771f0 e-flex e-con-boxed e-con e-parent\" data-id=\"19771f0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-a52af24 e-con-full e-flex e-con e-child\" data-id=\"a52af24\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"984b4a7\">GEL\u00c4NDEFORM<br>Pl\u00f6tzlicher Tod durch Hirnblutungen, Herzbeutelblutungen, Zwerchfellblutungen, Bauchfellblutungen<\/p>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c108baa e-con-full e-flex e-con e-child\" data-id=\"c108baa\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"1e9c347\">SUBKUTAN-CHRONISCHE FORM<br>Anorexie, Niedergeschlagenheit, Ersch\u00f6pfung, blasse Schleimh\u00e4ute, Unterk\u00fchlung, An\u00e4mie, Bewegungsst\u00f6rungen (H\u00e4matom, Haut- und intramuskul\u00e4re Blutungen), Nasenbluten, Bluterbrechen, Teerstuhl, Blut im Urin, Blutungen verschiedener Lokalisation<\/p>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-455b2ed e-con-full e-flex e-con e-child\" data-id=\"455b2ed\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"6e17aa2\">Tod oder R\u00fcckbildung der Symptomatik innerhalb von 1 \u2013 10 Tagen<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-08f4562 e-flex e-con-boxed e-con e-parent\" data-id=\"08f4562\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<h2 data-interaction-id=\"a58f640\" class=\"e-heading-base\">LOKALISIERUNG VON BLUTUNGEN<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e9f89dd e-flex e-con-boxed e-con e-parent\" data-id=\"e9f89dd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-0757b68 e-con-full e-flex e-con e-child\" data-id=\"0757b68\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"4c214e6\">Hund und Katze<br>Subkutanes Gewebe (besonders bei fetten Tieren), Lunge, Thymus, Mediastinum (H\u00e4matothorax, Epistaxis, Husten), perirenales Gewebe (H\u00e4matoperitoneum), Blase<\/p>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7faad53 e-con-full e-flex e-con e-child\" data-id=\"7faad53\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"5f2a841\">Schwein<br>Unterhautgewebe und Gelenke<\/p>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7751300 e-con-full e-flex e-con e-child\" data-id=\"7751300\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"1b6b34d\">V\u00f6gel<br>Unterhautgewebe, Zwischenrippenmuskeln, Eierst\u00f6cke<\/p>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7b9a771 e-con-full e-flex e-con e-child\" data-id=\"7b9a771\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"4ba387c\">Leprechaun<br>Unterhautgewebe, Gliedma\u00dfenmuskeln, Darm, Lunge<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-dd046bb e-flex e-con-boxed e-con e-parent\" data-id=\"dd046bb\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t<h2 data-interaction-id=\"3b40635\" class=\"e-heading-base\">BEHANDLUNG<\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-abfafcc e-flex e-con-boxed e-con e-parent\" data-id=\"abfafcc\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-32c511f e-con-full e-flex e-con e-child\" data-id=\"32c511f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"967c308\">Tiere ohne Symptome<br>Erbrechen herbeif\u00fchren: Apomorphin (Hund 0,05 \u2013 1 mg\/kg s.c. oder i.m.)<br>Pflanzenkohle Vitamin K oral<\/p>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7fc0afc e-con-full e-flex e-con e-child\" data-id=\"7fc0afc\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<p class=\"e-paragraph-base\" data-interaction-id=\"632f657\">Tier mit h\u00e4morrhagischem Syndrom<br>Unterst\u00fctzende Therapie: Fl\u00fcssigkeitszufuhr, Sauerstofftherapie, kardiiorespiratorische Stimulanzien<br>Antidottherapie: Vitamin K1 (Phytonadion) (Vitamin K3 inaktiv) Sto\u00dfdosis: 2-5 mg\/kg i.v. (bei Bedarf 2-3 Mal alle 12 Stunden wiederholen) s.c. und i.m. Wege kontraindiziert \u2013 rektaler Weg m\u00f6glich Erhaltungsdosis: 2-5 mg\/kg p.o. t\u00e4glich f\u00fcr 21 Tage wenn das Produkt nicht bekannt ist, 7 Tage Warfarin, 14 Tage Produkte der ersten Generation, 21 Tage Produkte der zweiten Generation, &gt;28 Tage Produkte der dritten Generation<br>Bluttransfusion \u2013 PPSB (teuer und schwer zu finden)<\/p>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2a0f738 e-flex e-con-boxed e-con e-parent\" data-id=\"2a0f738\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-72e582d elementor-widget elementor-widget-html\" data-id=\"72e582d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<iframe 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[&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","site-sidebar-layout":"no-sidebar","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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